Diabetic Foot Ulcers: Types, Causes, and Symptoms

  • Assoc. Prof. Dr. Aytaç Çetinkaya
  • May 4, 2025

Diabetic Foot Ulcers: Types, Causes, and Symptoms

Diabetic Foot Ulcers: Types, Causes, and Symptoms

Diabetic foot ulcers are a significant health problem that can lead to serious complications if left untreated. In this article, we will provide detailed information about the types, causes, and symptoms of diabetic foot ulcers.

Types of Diabetic Foot Ulcers

Diabetic foot ulcers are caused by nerve damage (diabetic neuropathy) and blood vessel problems due to prolonged high blood sugar levels in diabetic patients. The main types of diabetic foot ulcers are:

1. Neuropathic Ulcer

Nerve damage caused by diabetic neuropathy leads to loss of sensation in the foot. This can cause the patient to not notice small wounds on their feet. Neuropathic ulcers typically occur on the sole of the foot, toes, or heel and are often painless, but can become infected.

2. Ischemic Ulcer

In diabetic patients, poor blood flow (ischemia) can prevent oxygen and nutrients from reaching the cells in the foot, leading to tissue death. Ischemic ulcers typically occur on the toes or heel and manifest as discoloration, coolness, and non-healing wounds.

3. Mixed Ulcer (Neuropathic and Ischemic)

This type of ulcer is a combination of neuropathic and ischemic conditions. Both nerve damage and blood circulation problems contribute to the formation of these ulcers. The ulcer usually becomes infected and can lead to serious complications if left untreated.

4. Ulcerative Ulcer

Diabetic foot ulcers can occur due to excessive pressure, friction, or trauma. These ulcers typically occur on the sole of the foot or toes and can worsen if not properly treated, increasing the risk of infection.

5. Infected Ulcers

Diabetic foot ulcers can quickly become infected due to a weakened immune system. Infection is characterized by symptoms such as redness, swelling, heat, and foul odor. Infected ulcers can progress to bone if left untreated, leading to the need for amputation.

What is Diabetes and What Causes It?

Diabetes is a chronic disease characterized by the body’s inability to produce or effectively use insulin, leading to high blood sugar levels. Insulin is a crucial hormone that regulates blood sugar.

Causes of Diabetes

Type 1 Diabetes

  • Typically caused by genetic predisposition and immune system problems
  • The pancreas stops producing insulin
  • Usually begins in childhood or adolescence

Type 2 Diabetes

  • A condition characterized by insulin resistance and the pancreas’s inability to produce sufficient insulin
  • Main causes include:
    • Obesity
    • Sedentary lifestyle
    • Unhealthy diet
    • Genetic factors

Gestational Diabetes

  • High blood sugar levels during pregnancy
  • Blood sugar levels usually return to normal after delivery
  • Increases the risk of developing type 2 diabetes later in life

Complications Caused by Diabetes

If left untreated, diabetes can lead to the following health problems:

  • Heart diseases and stroke risk
  • Blood vessel problems and circulation disorders
  • Kidney damage and kidney failure
  • Nerve damage (diabetic neuropathy)
  • Vision loss and retinopathy
  • Diabetic foot ulcers and infections

Symptoms of Diabetic Foot Ulcers

Diabetic foot ulcers are open wounds that commonly occur on the feet of diabetic patients. These wounds are caused by nerve damage (neuropathy) and blood vessel problems (ischemia) resulting from diabetes.

Symptoms of Diabetic Foot Ulcers

  1. Pain and Sensitivity

    • Pain or sensitivity in the foot
    • Burning sensation
    • Numbness and tingling
    • Typically seen on the toes and sole of the foot
  2. Wound Formation

    • Cuts on the toes, heel, and sole
    • Ulcers (open wounds)
    • Wounds that grow if left untreated
  3. Infection Symptoms

    • Redness
    • Swelling
    • Heat increase
    • Bad odor
    • Pus discharge
  4. Skin Changes

    • Pale skin color
    • Discoloration
    • Signs of poor blood flow

Diabetic foot ulcers can be controlled with early diagnosis and appropriate treatment. Therefore, it is crucial to consult a healthcare professional if you notice any of the above symptoms.

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